Inno-Quarter (IQ) provides a new way to short track innovation processes and improve the cost-effectiveness of startup support mechanisms and redirect funds towards sustainable commercialisation of more innovations.NSRs score low in EU innovation indexes in terms of commercialisation. SMEs/entrepreneurs often lack the means to go beyond the development stage or fail soon after commercialisation. This because many companies initiate innovation processes in isolation within the company or an unsufficient network, which causes difficulties in attracting investors, finding potential customers, and acquiring raw resources to enlarge production.IQ will facilitate entrepreneurs with an integral public service (innovation quarter) that is organised at existing events. The innovation quarters should reduce the costs of conventional start-up programmes, by reducing the time needed to validate a product/service with 2 years. IQ will provide entrepreneurs with: (1) possibility to develop new products/services (2) end-user feedback for products/business models/services ready for market uptake (3) business support platform (4) enabler of product/service development.Quadruple helix partnerships of public authorities/development agencies, knowledge institutes, private partners and the community, represented by the IQ beneficiaries, will jointly develop, test and evaluate this service in several regions to come to a validated method available for adoption throughout the NSR.