The region has a rapidly ageing population, which is reflected in the rise in problems with serious joint wear. Joint replacement implants can offer a solution, but these generic implants have a limited life and therefore often have to be replaced themselves. There is a clear need for a new generation of medical implants, ideally specifically made for the anatomical form of the patient. PRosPERoS is responding to this need and aims to develop new patient-specific hip and back implants, which will accelerate and improve the healing process and therefore prevent infections. The basis for the research is the promising field of regenerative medicine, in which the patient's body is stimulated to regenerate damaged or removed tissue itself. 3D printed implants, anti-inflammatory and bone-growth stimulating coatings and new, resorbable biomedical materials will be developed. No fewer than five universities and teaching hospitals in the border region will be working together with companies such as Antleron and PCOTech, who have laboratories for conducting the preclinical research, but are also able to carry out the clinical studies in the final stage of the project. Companies such as Xilloc will be responsible for the design, production and commercialisation of implants and coating technologies. This will enable the emergence of a solid regenerative medicine network in the border region with regional knowledge centres, high-tech industry and academic-medical centres.