Who estimates that 13 million people will succumb to infections in 2050. In the last 10 years, 60 % of these diseases have been caused by the animal. To address the new challenges posed by infectious diseases internationally, the global health agencies (WHO, OIE and FAO) have proposed a “One Health” or “One Health” approach that takes into account the human-animal-environment interface. The major challenges are to prevent and cure infectious diseases while promoting the rational use of drug inputs that respect our environment. One of the greatest challenges facing humanity is the resistance that pathogens have developed against the available therapeutic arsenal (antibiotics and antivirals). An example is Mycobacterium tuberculosis bacille responsible for tuberculosis (TB), whose XDR strains ultra-resistant make any conventional treatment unnecessary. Influenza (IV) viruses responsible for influenza are another current scourge in human and veterinary medicine. They cause annual epidemics and frequent epizootic diseases. A constant fear is the appearance of avian influenza viruses (AIVs) capable of infecting humans. Resistance to antivirals is also high in IVs. It is therefore necessary to explore new ways to combat infections. Target metabolic pathways essential to the host to fight against...