The “Prometheas Energy Corridor” is an integrated high accessibility and extroversion Research Infrastructure, with a nationwide reach and international recognition that will be the field of development and experimental testing of innovative materials and processes for environmentally friendly and energy-efficient applications. The main mission of Promethea is to contribute to the creation of the critical bridge between the research and production sector, contributing to the effective transformation of the latter, through the exploitation of existing and new know-how and the high training of the technical and scientific potential of both sectors towards sustainable development and social well-being. Prometheas aims to create a solid basis for defining the procedures for effective integration of activities, through targeted upgrading of equipment and infrastructure related to reduced/zero carbon footprint energy processes, green mobility actions and advanced materials production methods and plants through the use of appropriate raw materials. Prometheus emphasises three areas: solar thermochemical technologies and the application of solar technologies in traditional energy production processes for the production of renewable energy carriers (from water, carbon dioxide, biomass and waste) in the form of liquid and gaseous fuels (ii) Innovative material technologies for the production of key elements of the reported chain such as high temperature reactors, catalysts, fuel cells, batteries, membranes, etc. (iii) Assessment of chain systems and subsystems with a focus on green mobility technologies (efficient and clean vehicles; intelligent transport systems, smart fleet management systems) as well as clean energy technologies (electricity, heat, clean water and combinations). Prometheas is an interdisciplinary platform for a wide range of potential users, both academic/research and industrial. The implementing bodies of Promethea are the National Centre for Research and Technological Development (CETET) and in particular the Particle and Aerosol Technology Laboratory of the Institute of Chemical Processes & Energy Resources (EDEP), having the role of Coordinator, and the National Centre for Natural Science Research “Democritos”, participating with the Laboratory of Solar and other Energy Systems of the Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety. The Institute of Environmental Fuels & Hydrocarbons, the Laboratory of Solid Fuel Technologies and Applications and the Institute of Sustainable Mobility and Transport Networks of CERTH also participate in Promethea. Users of the infrastructure include the Aristotle University of Thessaloniki, the University of Patras, the Technical University of Crete, the Centre for Renewable Energy Sources, the National Technical University of Athens and the University of Western Macedonia. In addition, a strong critical mass of industrial users from Greece and 11 countries abroad, with about 50 members, has already expressed its support for Promethea. In addition, 14 foreign research organisations have expressed their interest in cooperation within the proposed infrastructure. The socio-economic benefits that will be obtained have already been positively assessed by a number of state and local bodies supporting Promethea such as the Ministry of Macedonia-Thrace, the Ministry of National Defence, the Regions of Central and Western Macedonia, the Municipalities of Thessaloniki and Thermi, the Chamber of Commerce of Thessaloniki, the Hellenic Association of Exporters, the Association of Industries of Northern Greece, etc.