The main objective of this project is the establishment of an institution providing comprehensive, systematic support and expert advice for small and medium-sized entrepreneurs as well as for those interested in entrepreneurship (including disadvantaged social groups such as women, seniors/generation 50+, social and health handicaps, etc.), operating in the territory of the West Slovakia, Central Slovakia and Eastern Slovakia self-governing regions, with the exception of the Bratislava Self-Governing Region (BSK). Its essence is the construction and operation of the National Business Centres – one-stop-shop institutions located in the regions of Slovakia outside the BSK.  Its support, professionally guaranteed services are intended for business-seekers, early-stage enterprises or pre-existing, established enterprises that meet the SME criteria. A wide range of services provided in NPCs in the regions will consist of:  professional group activities – seminars, webinars, lectures, discussion forums, workshops, conferences, etc., providing short-term and long-term individual counselling, stays in a classic or virtual business incubator, participation in professional events and internships abroad, transfer of research and academic potential to the business environment, technological capacities within creative workshops of the project, information and popularisation activities for secondary and university schools and the general public aimed at increasing motivation to entrepreneurship, as well as comprehensive information on the possibilities of financing business activities or services of partner institutions. The NPC National Project in the Regions will draw on experience from the implementation of the NPC II-BA Region project, which is implemented as a model project of the future network of National Business Centres in the regions of the Slovak Republic.