Advancing Bone Regeneration with Synthetic, Animal-Free Biomaterials

Overview: FlexiOss® is a groundbreaking synthetic bone substitute developed by the Medical University of Lublin in Poland. Composed of hydroxyapatite—a mineral naturally found in bones and teeth—this biomaterial mimics human bone structure and is free from animal-derived components. Its design allows for easy shaping and adaptability during surgical procedures, enhancing bone regeneration and integration. European Commission

Objectives:

1. Enhance Surgical Outcomes: Provide surgeons with a versatile and effective material for bone defect reconstruction.
2. Promote Biocompatibility: Utilize materials that reduce the risk of rejection and eliminate the need for additional surgeries.
3. Expand Market Reach: Introduce an animal-free bone substitute suitable for diverse cultural and medical requirements.

Key Features:

• Malleable Structure: Resembling pumice stone, FlexiOss® can be easily cut and, when moistened, molded to fill various bone cavities.
• Porous Composition: Its structure facilitates the absorption of blood and medications, supporting the ingrowth of bone cells and natural tissue regeneration.
• Animal-Free: The absence of animal-derived products makes it suitable for patients with specific cultural or medical considerations.

Target Audience:

• Orthopedic and Craniofacial Surgeons: Professionals seeking advanced materials for bone reconstruction.
• Patients Requiring Bone Repair: Individuals needing bone defect treatments, including those with cultural sensitivities to animal-derived products.
• Medical Device Distributors: Companies aiming to offer innovative, biocompatible bone substitutes in the European market.

Impact: FlexiOss® has been successfully implanted in 41 patients during experimental procedures, demonstrating its efficacy in bone regeneration. Notably, it has been used to replace a 7-centimeter bone fragment in a patient at risk of amputation, effectively saving the limb. PARP

Recognitions and Awards:

• Polish Product of the Future Award: FlexiOss® received this accolade, highlighting its innovative contribution to medical technology. PARP
• Multiple Patents: The technology is protected by three patents, underscoring its uniqueness and innovative design. European Commission

Additional Resources: For more information, visit the FlexiOss® official website.